Preventing Basal Cell Carcinoma formation by targeting the tumor environment
Grantee: Associate Professor Kiarash Khosrotehrani, University of Queensland
Amount: AUD 415,386
Grant category: Research Grants
Year: 2015
Geography: Australia
In this study, Associate Professor Kiarash Khosrotehrani of The University of Queensland in Australia proposes to better characterise the molecular nature of the factors provided by fibroblasts to support basal cell carcinoma (BCC) growth in vivo in order to find new targets for therapies that would prevent BCC development. He and his team will also show proof of principle demonstrating that targeting this process can actually prevent BCC development.
These findings have the potential to translate in effective prevention strategies, allowing field therapy of normal looking skin to avoid the development of new BCCs. Such finding will have strong health benefits in terms of morbidity associated with multiple surgeries, years of healthy life enjoyed by individuals and finally in terms of economic cost.
The LEO Foundation Scholarship for Dermatological Research
Grantee: Scholarship programme
Amount: DKK 2,200,000
Grant category: Research Grants
Year: 2012
Geography: Australia, Denmark
The LEO Foundation Scholarship for Dermatological Research aims to strengthen research collaboration within the field of skin cancer between Australia and Denmark by supporting training of and research by young scientists.
One scholarship is offered annually on behalf of the LEO Foundation, alternating between Australia and Denmark.
A candidate from Australia travels to work within a Danish tertiary institution and a Danish student is selected with a view to joining an Australian campus.
The funds received may be used as part of an ongoing PhD project or for postdoctoral research. The funds must in part support a research/educational stay in Australia of at least six months for the Danish student.
Publications
Automated detection of actinic keratoses in clinical photographs
Hames SC, Sinnya S, Tan JM, Morze C, Sahebian A, Soyer HP, Prow TW.
PLoS One. 2015 Jan 23;10(1):e0112447. doi: 10.1371/journal.pone.0112447. eCollection 2015
Counting actinic keratosis – is photographic assessment a reliable alternative to physical examinations in clinical trials?
Sinnya S, O’Rourke P, Ballard E, Tan JM, Morze C, Sahebian A, Hames SC, Prow TW, Green AC, Soyer HP.
Acta Derm Venerol. 2015 May;95(5):604-5. doi: 10.2340/00015555-2040. No abstract avaliable
The future of keratinocyte skin cancer surveillance: automated image analysis to identify and monitor keratinocyte dysplasia
Hames SC, Prow TW.
Curr Probl Dermatol. 2015;46:77-84. doi: 10.1159/000366540. Epub 2014 Dec 18
Automated segmentation of skin strata in reflectance confocal microscopy depth stacks
Hames SC, Ardigò M, Soyer HP, Bradley AP, Prow TW.
PLoS One. 2016 Apr 18;11(4):e10153208. doi: 10.1371/journal.pone.0153208. eCollection 2016.
Automated detection of actinic keratoses in clinical photographs
Hames SC, Sinnya S, Tan JM, Morze C, Sahebian A, Soyer HP, Prow TW.
PLoS One. 2015 Jan 23;10(1):e0112447. doi: 10.1371/journal.pone.0112447. eCollection 2015.
Counting actinic keratosis – is photographic assessment a reliable alternative to physical examination in clinical trials?
Sinnya S, O’Rourke P, Ballard E, Tan JM, Morze C, Sahebian A, Hames SC, Prow TW, Green AC, Soyer HP.
Acta Derm Venereol. 2015 May;95(5):604-5. doi: 10.2340/00015555-2040. No abstract available.
The future of keratinocyte skin cancer surveillance: automated image analysis to identify and monitor keratinocyte dysplasia
Hames SC, Prow TW.
Curr Probl Dermatol. 2015;46:77-84. doi: 10.1159/000366540. Epub 2014 Dec 18
Anatomical skin segmentation in reflectance confocal microscopy with weak labels*
Hames SC, Ardigò M, Soyer HP, Bradley AP, Prow TW.
http://ieeexplore.ieee.org/xpls/abs_aa.jsp?arnumber=7371231&tag=1
* This won the Canon Extreme Imaging Competition (DICTA category) prize in late 2015
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