Increased scientific collaboration and networking on skin immunology and allergies in skin of color
Grantee: Associate Professor Charlotte Bonefeld, University of Copenhagen
Amount: DKK 394,170
Grant category: Research Networking
Year: 2025
Geography: Denmark
Contact Dermatitis (CD) are common skin diseases caused by exposure of the skin to chemicals. While widely studied in Europe, CD is often overlooked in Sub-Saharan African countries. To improve prevention and treatment globally, we need better understanding of how CD appears in different skin types and regions. The European Society of Contact Dermatitis (ESCD) will host its 2026 congress in Copenhagen from June 24–27. A pre-symposium titled “Novel Understanding of Skin Allergies” will highlight recent advances in skin immunology and increase the focus on the immune responses that leads to CD worldwide. Moreover, the main program at the ESCD congress will include the workshop ‘Patch Tests on Skin of Color’ and a focus session on ’Eczema in Sub-Saharan Africa’. The Research Networking Grant will cover expenses to the pre-symposium and 10 travel grants to researchers from Sub-Saharan African countries. For more details, visit the event website.
Epidermolytic Ichthyosis Global Symposium
Grantee: Helen Lill, EI Cure Project
Amount: DKK 158,000
Grant category: Research Networking
Year: 2025
Geography: Switzerland
The EI Cure Project and EI Cure Project Research Alliance will host a 2-day symposium dedicated entirely to rare genetic skin disease Epidermolytic Ichthyosis. The symposium will be held at the Zurich Careum, Switzerland from March 19th to 20th. The full-day presentations, for interested individuals and coming researchers, include the following themes:
- Patient and Parent Perspectives
- Clinical Classifications and Current Care
- Proteomics and Drug-Repurposing
- Gene-Editing Research Updates
The 18th International Workshop on Langerhans Cells #LC2025
Grantee: Associate Professor Eynav Klechevsky, Washington University in St. Louis
Amount: DKK 499,812
Grant category: Research Networking
Year: 2025
Geography: USA
The 18th International Workshop of Langerhans Cells and Related Myeloid Cells in the Skin will take place on September 3–5, 2025, at Washington University in St. Louis. This global scientific meeting brings together researchers to explore the biology and interaction of immune cells in the skin – how they protect us, how they contribute to diseases like eczema, psoriasis, and skin cancer, and how they can be targeted for new treatments. The workshop fosters discovery, collaboration, and innovation in skin science, with talks by leading scientists, and early-career researchers, males and females from around the world. Read more information here.
72nd Annual Montagna Symposium on the Biology of Skin: Mechanistic Insights into Emerging Therapeutic Platforms
Grantee: Professor Sancy Leachman, Oregon Health and Science University
Amount: DKK 221,290
Grant category: Research Networking
Year: 2025
Geography: USA
The 72nd Annual Montagna Symposium will be held October 16th-20th on the Oregon Coast. The symposium will focus on emerging paradigms in personalized medicine.
Population studies have raised questions about why individuals do not respond to established therapies. Patients are individuals with personalized social, behavioral, and genetic determinants, but knowledge gaps exist regarding how these determinants influence diagnosis and treatment of cutaneous diseases. The goal is to highlight emerging avenues of investigation and streamline their incorporation into clinical medicine.
This event is designed for senior and junior level leaders in the field: scientists, dermatology clinicians, clinical, translational and basic science researchers, and trainees. The format includes lectures, discussions, and many networking opportunities which enable interaction between new and established scientists and dermatologists. Visit the website for the program and registration.
Developing Bioluminescent Madurella mycetomatis for Breakthrough Drug Discovery in a Novel Skin Model of Eumycetoma
Grantee: Wendy Laureijssen-van de Sande, Associate professor, ErasmusMC, Netherlands
Amount: DKK 3,999,996
Grant category: Research Grants
Year: 2025
Geography: Netherlands
Mycetoma is one of the world’s most neglected diseases – a slow growing skin infection that causes severe pain and deformities. It affects people in poor, rural areas across more than 20 countries, spanning five continents. The fungal form, eumycetoma, can lead to lifelong disability, and, in many cases, amputation. It is often accompanied by social stigma and mental health challenges, further isolating patients. Current treatments are toxic, unaffordable, and must be taken for up to a year – often with poor results. One major reason better treatments haven’t been developed is that there is no reliable way to test new drugs before trying them on humans. Wendy Laureijssen-van de Sande’s project will develop the first mouse model that closely mimics the human form of the disease. This will enable researchers to test new antifungal compounds more safely and effectively, laying the path for better, faster and more affordable treatments for patients who urgently need them.
Uncovering the cause of treatment resistance in autoimmune blistering disease
Grantee: Joanne Reed, Associate Professor, The University of Sydney, Australia
Amount: DKK 3,902,405
Grant category: Research Grants
Year: 2025
Geography: Australia
Autoimmune bullous disease is a condition where the patient’s immune system attacks their skin, causing painful blistering. Some patients develop blisters in the mouth, leading to difficulty eating and malnutrition or inflammation in the eye, which can cause blindness. There is no cure. Treatment involves suppressing the immune system but can lead to side effects and increased infections. Joanne Reed’s research will use new technology to investigate patient blood and skin samples left over from biopsies performed for diagnosis. The technology enables patient samples to be evaluated at an unprecedented level of detail to identify and study the immune cells and genes responsible for disease. This information will be used to develop a test that can predict patients at risk of severe symptoms to enable early intervention before permanent organ damage occurs. The detailed analysis of the disease-causing cells will also inform the development of new drugs that can specifically target these cells.
Exploring neutrophil metabolism as a therapeutic target in pyoderma gangrenosum
Grantee: Samreen Jatana, Staff Research Associate, Cleveland Clinic, United States
Amount: DKK 2,717,547
Grant category: Research Grants
Year: 2025
Geography: USA
Pyoderma gangrenosum (PG) is a rare skin disease. Patients with PG have defects in their skin wound healing responses. Even minor injuries and cuts to the skin can form large chronic ulcers. PG ulcers are enriched with neutrophils, an immune cell type that plays a vital role in skin wound healing. Typically, neutrophils travel to the skin right after an injury, perform their tasks, and leave within a period of 3 days. Samreen Jatana wants to understand why PG neutrophils don’t perform their regular tasks and impair wound healing in skin. Samreen Jatana and her colleagues analyzed peripheral blood from patients with PG and identified a type of neutrophil in circulation with features of immature neutrophils that typically live in the bone marrow. They anticipate that this neutrophil subset cannot utilize energy properly and might be exhausted to perform its function. In this project, they will study this neutrophil subset to understand if it can be targeted therapeutically to treat PG.
Immune Dynamics in Keloid-Prone Skin: Mechanisms of Inflammation and Fibrosis
Grantee: George Agak, Associate Professor, The Regents of the University of California, Los Angeles, United States
Amount: DKK 3,998,784
Grant category: Research Grants
Year: 2025
Geography: USA
Keloids are raised, inflamed scars that grow beyond the original wound, often becoming painful and disfiguring. They disproportionately affect African American, Hispanic/Latino, and Asian individuals, yet the biological reasons behind their formation remain unclear. Current treatments are limited, with high recurrence rates. George Agak’s research aims to uncover the molecular drivers of keloids by studying skin cells from keloid-prone individuals at the single-cell level. George Agak and his team focus on a key signaling pathway, the ACE-ASPN axis, which appears to promote inflammation and excessive scar formation. By using cutting-edge technologies like scRNA-seq, spatial-seq and advanced machine-learning tools, they will map how keloids develop across diverse skin types. Additionally, they will test whether angiotensin receptor blockers (ARBs)—drugs already used for high blood pressure—can reduce keloid growth. The goal is to identify targeted treatments, leading to personalized therapies for those most affected.
Novel treatment for accelerating wound healing with AI-driven, de novo designed proteins blocking Granzyme K
Grantee: Sine Hadrup, Professor, Head of Section, Technical University of Denmark, Denmark
Amount: DKK 3,982,500
Grant category: Research Grants
Year: 2025
Geography: Denmark
Chronic skin wounds and burns are major healthcare challenges, often healing slowly and leading to infections, pain, and high medical costs. Sine Hadrup’s project focuses on an enzyme that may worsen inflammation and delay healing of the injured skin. Sine Hardrup and her team will use artificial intelligence-driven protein design to create a small protein inhibitor (miBd) that blocks the enzyme, preventing its harmful effects. First, they will test whether miBds can bind and stop enzyme activity. Then, they will evaluate their impact on wound healing using human cell culture. Finally, they will test them in a pig skin model, as pig skin closely resembles human skin. Burns are introduced on the pig skin and treated topically with or without the miBds. If successful, this research could lead to new treatment options for wound healing and inflammatory skin diseases like psoriasis, offering better patient outcomes and faster recovery times.
Improving Outcome Measurement in Fibrosing Skin Disorders
Grantee: Adela Cardones, Chief, Division of Dermatology, University of Kansas Medical Center Research, United States
Amount: DKK 3,978,779
Grant category: Research Grants
Year: 2025
Geography: USA
Sclerodermatous chronic graft-versus-host disease is a common, debilitating side effect that can develop in patients who have undergone hematopoietic stem cell transplantation for blood cancer. It is challenging to treat and usually requires medications that suppress the immune system. One of the biggest challenges in treating patients with cGVHD is the lack of an accurate informative way for doctors to know if the skin is responding to therapy or is getting worse. In this project, Adela Cardones will use novel ultrasound technologies to measure changes in skin stiffness among cGVHD patients over a 1-year period. Adela Cardona and her team will compare this with using traditional clinical assessment, patient reported symptoms, and blood and skin markers of inflammation. If successful, this will allow them to better detect worsening or improvement of skin thickening and stiffness. This will ultimately lead to better care of patients and allow discovery of better treatments.