Search Results for The Science Olympiads
Jesper Brandgaard new Chairman of the Board of Directors of LEO Pharma
…therapies and a pioneering spirit. Founded in 1908, LEO Pharma has devoted decades of research and development to advance the science of dermatology, setting new standards of care for people…
The LEO Foundation announces closing of Nordic Capital’s investment in LEO Pharma
…robust R&D pipeline, a wide range of therapies and a pioneering spirit. Founded in 1908, LEO Pharma has devoted decades of research and development to advance the science of dermatology,…
Award winner with a curious mind combines sophisticated technology with excellent skin research
…e.g., JID, FASEB J, Nature, Cell and Science Translational Medicine. Beate Lichtenberger Principal Investigator, the Medical University of Vienna, Austria 2016 – present Principal Investigator at the Skin & Endothelium…
Positional Information and Repair of Skin Injury
Grantee: Peter Reddien, Professor, Whitehead Institute, Cambridge
Amount: DKK 2,498,235
Grant category: Research Grants in open competition
Year: 2021
Geography: USA
The project aims to investigate if an untapped potential for true skin regeneration exists in vertebrates not known to have the capacity to regrow skin tissue. If indeed such capacity exists and if it can be reactivated it may be possible to regenerate fully functional skin without any scarring.
Peter Reddien and his team at Whitehead Institute will look at the so-called “regional identity” of new cells which is central to regeneration in many animals capable of regeneration. They will use sophisticated techniques like single-cell RNA sequencing and spatial transcriptomics to compare factors and signaling pathways central to development in skin. Mouse skin – a vertebrate not known to be able to regenerate – and skin from a special regenerative salamander (axolotl) are used as models.
Peter Reddien’s research project is a basic skin science project with a novel approach to understanding the skin’s potential for regeneration.
Young Scientists Program
Grantee: Japanese Society for Investigative Dermatology
Amount: EUR 15,000
Grant category: Education and Awareness Grants
Year: 2019
Geography: Japan
The mission of the Japanese Society for Investigative Dermatology (JSID) is to advance the position of dermatology in the interdisciplinary world and to enhance the quality of science and research presentations in dermatology for the purposes of maintaining healthy skin and further advancing the treatment of skin diseases.
12th JSID Young Academician-Fostering Seminar (Kisaragi Juku)
Grantee: Japanese Society for Investigative Dermatology
Amount: EUR 15,000
Grant category: Education and Awareness Grants
Year: 2021
Geography: Japan
The mission of the Japanese Society for Investigative Dermatology (JSID) is to advance the position of dermatology in the interdisciplinary world and to enhance the quality of science and research presentations in dermatology for the purposes of maintaining healthy skin and further advancing the treatment of skin diseases.
What if our immune system holds the secret to preventing skin cancer?
…his continuous work and close dialogue with patients. And when asked what has shaped and inspired his career in science so far, Dr. Demehri highlights his dedication and passion for…
Investigating the role of immune-olfactory signaling in inflammatory skin disease
Grantee: Joshua Moreau, Assistant Professor, Oregon Health and Science University
Amount: DKK 3,717,163
Grant category: Serendipity Grants
Year: 2025
Geography: USA
Organisms are continuously bathed in a rich milieu of olfactory compounds. Defined by their ability to elicit the sense of smell, these molecules, and the receptors that sense them, have profound biological importance. Humans have hundreds of olfactory receptors, but paradoxically these are often expressed outside of the nasal cavity and on immune cells. Their function in these contexts is almost entirely unknown. The serendipitous finding illustrates that: a) olfactory receptors are enriched in inflamed skin and on lesion infiltrating lymphocytes; and b) odorants directly modulate lymphocyte function. Understanding the role and molecular mechanisms of these pathways in inflammation may open new avenues for treating skin disease with promise for targeted topical approaches.
To explore this serendipitous finding, the research project will combine in vivo models of skin inflammation with expertise in multiomic analyses of hidradenitis suppurativa (HS) and pyoderma gangrenosum (PG) patient tissues. The study will determine if exposure to olfactory molecules modulates skin inflammation in vivo, functionally dissect immune cell intrinsic olfactory signaling, and identify signatures of pathway activity in HS and PG.
This work will provide insight into the fundamental biology of immune-olfactory signaling and determine if there is functional relevance for skin inflammation. The project will also test the implications for HS and PG, where novel therapeutic approaches are urgently needed.