Search Results for The Science Olympiads
Investigating the role of immune-olfactory signaling in inflammatory skin disease
Grantee: Joshua Moreau, Assistant Professor, Oregon Health and Science University
Amount: DKK 3,717,163
Grant category: Serendipity Grants
Year: 2025
Geography: USA
Organisms are continuously bathed in a rich milieu of olfactory compounds. Defined by their ability to elicit the sense of smell, these molecules, and the receptors that sense them, have profound biological importance. Humans have hundreds of olfactory receptors, but paradoxically these are often expressed outside of the nasal cavity and on immune cells. Their function in these contexts is almost entirely unknown. The serendipitous finding illustrates that: a) olfactory receptors are enriched in inflamed skin and on lesion infiltrating lymphocytes; and b) odorants directly modulate lymphocyte function. Understanding the role and molecular mechanisms of these pathways in inflammation may open new avenues for treating skin disease with promise for targeted topical approaches.
To explore this serendipitous finding, the research project will combine in vivo models of skin inflammation with expertise in multiomic analyses of hidradenitis suppurativa (HS) and pyoderma gangrenosum (PG) patient tissues. The study will determine if exposure to olfactory molecules modulates skin inflammation in vivo, functionally dissect immune cell intrinsic olfactory signaling, and identify signatures of pathway activity in HS and PG.
This work will provide insight into the fundamental biology of immune-olfactory signaling and determine if there is functional relevance for skin inflammation. The project will also test the implications for HS and PG, where novel therapeutic approaches are urgently needed.
Eczema and Psoriasis Research Incubator: Cross-Disciplinary Innovation Forum
Grantee: Professor Peter van de Kerkhof, Chief Medical Officer, on behalf of the International Psoriasis Council
Amount: DKK 393,617
Grant category: Research Networking
Year: 2025
Geography: Germany
The Eczema and Psoriasis Research Incubator will be held on September 16, 2026, adjacent to the ESDR annual meeting in Heidelberg, Germany. This workshop is designed to accelerate progress in the understanding and treatment of psoriasis and eczema by fostering cross-disease and cross-disciplinary collaboration with patients, doctors, and researchers. Through interactive small-group challenge labs, participants will co-develop innovative research ideas with the potential to inform future multicenter studies, biomarker discovery, and precision medicine approaches. Dedicated opportunities for early-career researchers to showcase their work and facilitate their involvement in collaborations will ensure equitable participation and strengthen the global research pipeline. Open to international attendees, this incubator is intended as a launchpad for collaborative science, generating new ideas, networks, and frameworks to advance patient-centered skin research.
Award winner with a focus on alopecia areata
…Graduate School of Medical Science and Engineering, KAIST, Daejeon, Korea 2016 – 2018: Ph.D., (Dermatology) Chung-Ang University Hospital, Seoul, Korea 2014 – 2018: Resident, Department of Dermatology, Chung-Ang University Hospital,…
Award winner broadening our understanding of the genetics behind atopic dermatitis
…researchers in skin science. Chief Scientific Officer, Anne-Marie Engel, is delighted to be able to support Lavina’s research: “Lavinia Paternoster’s research into the genetic landscape of skin diseases is of…
Young Scientists Program
Grantee: Japanese Society for Investigative Dermatology
Amount: EUR 15,000
Grant category: Education and Awareness Grants
Year: 2019
Geography: Japan
The mission of the Japanese Society for Investigative Dermatology (JSID) is to advance the position of dermatology in the interdisciplinary world and to enhance the quality of science and research presentations in dermatology for the purposes of maintaining healthy skin and further advancing the treatment of skin diseases.
Education and Awareness Grants (round 3)
The LEO Foundation Award 2010 – Gold Award
Grantee: Dr. Jacob Pontoppidan Thyssen
Amount: DKK 1,000,000
Grant category: LEO Foundation Awards
Year: 2010
Geography: Denmark
Presented to young Danish dermatology researcher and MD Jacob Pontoppidan Thyssen for his important contributions to the field of skin disease and contact allergy science.
Dr. Thyssen’s research provides conclusive evidence that the Danish initiative to regulate nickel exposure, started in 1990, has succeeded in decreasing the prevalence of nickel allergy in Danish women. His findings, published in The New England Journal of Medicine last year, hold global relevance and may contribute to interventions in other nations, including the US.
Ownership
…research and development to advance the science of dermatology, setting new standards of care for people with skin conditions. LEO Pharma headquarters Visit LEO Pharma The LEO Group The LEO…
Publications
Publications Annual Reports Click to view Annual Report 2024 Key figures 2024 LEO Foundation_AR2023_finalAnnual Report 2023 LEO Foundation_AR_2022Annual Report 2022 LEO-Foundation_Annual-Report-2021_web-1Annual Report 2021 LEO-Foundation_Annual_Report_2020Annual Report 2020 LEO-Foundation-Annual-Report-2019Annual Report 2019 LEO_Foundation_Annual_Report_2018Annual…
Excellence in wound healing leads to the LEO Foundation Award
…Landén the LEO Foundation Award in recognition of her outstanding research. She is a highly skilled, passionate and productive young scientist with major accomplishments that will positively impact future science.”…