Association Between Serum Immunoreactivity and Inflammatory Cell Activation in Patients with Behçet’s Disease
Grantee: Tayfun Hilmi Akbaba, Research Assisstant, Hacettepe University, Türkiye
Amount: DKK 1,569,000
Grant category: LEO Foundation Visiting Researchers
Year: 2026
Geography: Türkiye
Behçet’s disease is a chronic inflammatory condition that commonly causes recurring skin and mouth lesions, significantly affecting patients’ quality of life. The reasons why the immune system becomes overactive are not fully understood. This project aims to investigate whether substances circulating in the blood of patients contribute to immune cell activation and inflammation. By comparing blood samples from patients with Behçet’s disease and healthy individuals, we will explore blood over-immune activity and effects on skin involvements. Understanding these mechanisms may help explain why some patients experience more severe or persistent disease. The findings may help identify blood-based indicators of disease activity and support the development of more targeted treatments for inflammatory diseases.