{"id":4646,"date":"2021-10-04T13:05:00","date_gmt":"2021-10-04T11:05:00","guid":{"rendered":"https:\/\/leo-foundation.org\/en\/?p=4646"},"modified":"2021-10-04T14:42:09","modified_gmt":"2021-10-04T12:42:09","slug":"the-leo-foundation-awards-dkk-14-million-to-five-new-skin-research-projects","status":"publish","type":"post","link":"https:\/\/leo-foundation.org\/en\/2021\/10\/04\/the-leo-foundation-awards-dkk-14-million-to-five-new-skin-research-projects\/","title":{"rendered":"The LEO Foundation awards DKK 14 million to five new skin research projects"},"content":{"rendered":"\n<div style=\"height:56px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><em>4 October 2021<\/em><\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:66.66%\"><div class=\"text-cols text-cols-columns-1 text-cols align\" data-block_60361a133b80a>\n  \n\n<p><strong>Can a mouse regrow damaged skin like a salamander can? Can we find a way towards scar-free wound healing? And can bacteria exchange treat acne while avoiding the issue of antibiotic resistance?<\/strong><\/p>\n\n\n\n<p>These are just some of the questions in five new research projects awarded under the LEO Foundation\u2019s open competition program, which aims to support the best skin research projects worldwide.<\/p>\n\n\n\n<p>With grant amounts up to DKK 3.7 million five researchers from Whitehead Institute for Biomedical Research, Helmholtz Zentrum M\u00fcnchen, Medical University of Vienna, Bispebjerg Hospital and Aarhus University are receiving grants totaling DKK 14 million for ambitious research projects.<\/p>\n\n\n\n<p>The projects span a wide range of focus areas, disciplines, approaches, and borders. From skin disorders we all know \u2013 like wounds, scars, and acne \u2013 to less known skin disorders \u2013 like hidradenitis suppurativa, cutaneous lupus erythematosus and lichen planus. From basic and translational research to clinical application. From bench-to-bedside. From USA to Germany, Austria, and Denmark.<\/p>\n\n\n\n<p>\u201cThe common thread linking the five new projects is that they all increase our knowledge of the skin and its diseases \u2013 by improving the fundamental understanding of the skin, by identifying new innovative treatments and by developing novel and improved diagnostics,\u201d says Ida Brams, Chief Grant Officer at the LEO Foundation, adding:<\/p>\n\n\n\n<p>\u201cMore than 3,000 skin diseases are known today, but many of the mechanisms driving these diseases are still unsolved scientific mysteries. Much more research is required to improve the understanding and treatment of the skin and its diseases.&nbsp;This is exactly what the LEO Foundation aims to do with its philanthropic activities.\u201d<\/p>\n\n\n<\/div>\n\n<style type=\"text\/css\">\n  [data-block_60361a133b80a] p {\n    column-count: 1;\n    column-gap: 30px;\n  }\n<\/style>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:19px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">Research projects selected for funding<\/h3>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><div class=\"text-cols text-cols-columns-1 text-cols align\" data-block_603616583b808>\n  \n<\/div>\n\n<style type=\"text\/css\">\n  [data-block_603616583b808] p {\n    column-count: 1;\n    column-gap: 30px;\n  }\n<\/style>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\"><div class=\"block-accordion-element accordion align\" data-block_615424d5e448b>\n  <div class=\"row\">\n    <div class=\"offset-md-2 offset-lg-2 offset-xl-3 col-sm-8 col-md-6 col-lg-6 col-xl-5 border-wt pl-0 order-1\">\n      <div class=\"d-flex flex-row align-items-center h-100\">\n        <button type=\"button\" class=\"btn btn-collapse collapsed p-0 mr-3\" data-toggle=\"collapse\" data-target=\"#collapse-block_615424d5e448b\" title=\"Click to expand\"><\/button>\n        <div class=\"d-flex flex-column justify-content-center\">\n          <h3>Georg Stary<\/h3>\n                      <h5>Associate Professor, Medical University of Vienna, Austria, DKK 3,1m<\/h5>\n                  <\/div>\n      <\/div>\n    <\/div>\n    <div class=\"col-sm-8 col-md-6 col-lg-6 col-xl-5 border-wt pr-0 order-sm-first order-first order-sm-2\">\n      <img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"1024\" src=\"https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Georg-Stary-768x1024.png\" class=\"w-100 h-auto\" alt=\"\" srcset=\"https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Georg-Stary-768x1024.png 768w, https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Georg-Stary-225x300.png 225w, https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Georg-Stary-1152x1536.png 1152w, https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Georg-Stary-960x1280.png 960w, https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Georg-Stary.png 1200w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \/>\n    <\/div>\n    <div class=\"offset-md-2 offset-lg-2 offset-xl-3 col-sm-16 col-md-12 col-lg-12 col-xl-10 py-4 px-0 collapse fade out order-3\" id=\"collapse-block_615424d5e448b\">\n      <p><strong>T-cell \u2013 keratinocyte interactions as therapeutic targets in lichenoid and interphase dermatoses<\/strong><\/p>\n<p>The aim of this project is to investigate the crosstalk between T-cells (TC) and keratinocytes (KC) and its role in two less explored inflammatory skin diseases, namely cutaneous lupus erythematosus and lichen planus. Specifically, the role of co-receptor stimulation or inhibition of T-cells will be investigated.<\/p>\n<p>The researchers hypothesize that skin diseases with prominent infiltration of pathogenic CD8+ T cells (cells that attack and kill other cells \u2013 including keratinocytes in autoimmune diseases) are related to an imbalance of activating and inhibitory signals on T cells determining the extent of the T-cell\u2013keratinocyte (TC\u2013KC) crosstalk.<\/p>\n<p>The team will investigate this using skin biopsies from patients to map TC\u2013KC receptor-ligand interactions by single-cell and spatial transcriptomics. They will then assess the properties of candidate receptors and decipher their mechanism of action by immunofluorescent imaging.<\/p>\n<p>While inhibitory T-cell co-receptors are already targeted for cancer immunotherapy, their therapeutic potential in T-cell-driven inflammatory disorders remains to be established. This study may provide the rationale to design T-cell-targeting therapies in inflammation and is particularly strong with its basis on patient material.<\/p>\n\n    <\/div>\n    <div class=\"offset-md-2 offset-lg-2 offset-xl-3 col-sm-16 col-md-12 col-lg-12 col-xl-10 border-wb order-4\"><\/div>\n  <\/div>\n<\/div>\n\n\n\n<div style=\"height:42px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"block-accordion-element accordion align\" data-block_6154251ae448c>\n  <div class=\"row\">\n    <div class=\"offset-md-2 offset-lg-2 offset-xl-3 col-sm-8 col-md-6 col-lg-6 col-xl-5 border-wt pl-0 order-1\">\n      <div class=\"d-flex flex-row align-items-center h-100\">\n        <button type=\"button\" class=\"btn btn-collapse collapsed p-0 mr-3\" data-toggle=\"collapse\" data-target=\"#collapse-block_6154251ae448c\" title=\"Click to expand\"><\/button>\n        <div class=\"d-flex flex-column justify-content-center\">\n          <h3>Holger Br\u00fcggemann<\/h3>\n                      <h5>Associate Professor, Aarhus University, Denmark, DKK 2,2m<\/h5>\n                  <\/div>\n      <\/div>\n    <\/div>\n    <div class=\"col-sm-8 col-md-6 col-lg-6 col-xl-5 border-wt pr-0 order-sm-first order-first order-sm-2\">\n      <img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"1024\" src=\"https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Holger-768x1024.png\" class=\"w-100 h-auto\" alt=\"\" srcset=\"https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Holger-768x1024.png 768w, https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Holger-225x300.png 225w, https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Holger-1152x1536.png 1152w, https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Holger-960x1280.png 960w, https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Holger.png 1200w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \/>\n    <\/div>\n    <div class=\"offset-md-2 offset-lg-2 offset-xl-3 col-sm-16 col-md-12 col-lg-12 col-xl-10 py-4 px-0 collapse fade out order-3\" id=\"collapse-block_6154251ae448c\">\n      <p><strong>PACT: Personalizing Acne Treatment Using Skin Microbiota Transplantation<\/strong><\/p>\n<p>This project aims to investigate the potential of using bacteria exchange or \u201cmicrobiome transplant\u201d as a viable treatment option for acne vulgaris.<\/p>\n<p>Acne vulgaris remains one of the most prevalent skin conditions worldwide affecting close to 10% of the population and impacting the quality of life of millions of people. Multiple factors contribute to acne, including genetics, excess sebum production, colonization of the skin by Cutibacterium acnes and an inflammatory cascade. Current treatments for acne such as retinoids and antibiotics have varied outcomes and side effects. As antibiotic resistance becomes an increasing concern in clinical practice, there is an unmet need for alternative treatment approaches.<\/p>\n<p>The team have previously identified a range of bacterial strains, isolated from healthy skin, that can selectively inhibit acne-associated Cutibacterium acnes strains. The current project takes a microbiome transplantation approach to acne treatment, utilizing a pre-existing in-house library of more than 1000 bacterial strains and testing their ability to modulate the skin microbiome and reduce acne symptoms in patients with mild-to-moderate acne.<\/p>\n<p>This project may pave the way for developing a personalized treatment to a very common skin disease while avoiding the issue of antibiotic resistance.<\/p>\n\n    <\/div>\n    <div class=\"offset-md-2 offset-lg-2 offset-xl-3 col-sm-16 col-md-12 col-lg-12 col-xl-10 border-wb order-4\"><\/div>\n  <\/div>\n<\/div>\n\n\n\n<div style=\"height:42px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"block-accordion-element accordion align\" data-block_60361d543b80f>\n  <div class=\"row\">\n    <div class=\"offset-md-2 offset-lg-2 offset-xl-3 col-sm-8 col-md-6 col-lg-6 col-xl-5 border-wt pl-0 order-1\">\n      <div class=\"d-flex flex-row align-items-center h-100\">\n        <button type=\"button\" class=\"btn btn-collapse collapsed p-0 mr-3\" data-toggle=\"collapse\" data-target=\"#collapse-block_60361d543b80f\" title=\"Click to expand\"><\/button>\n        <div class=\"d-flex flex-column justify-content-center\">\n          <h3>Peter Reddien<\/h3>\n                      <h5>Professor, Whitehead Institute, Cambridge, USA, DKK 2,5m<\/h5>\n                  <\/div>\n      <\/div>\n    <\/div>\n    <div class=\"col-sm-8 col-md-6 col-lg-6 col-xl-5 border-wt pr-0 order-sm-first order-first order-sm-2\">\n      <img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"1024\" src=\"https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Peter-Reddien-768x1024.png\" class=\"w-100 h-auto\" alt=\"\" srcset=\"https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Peter-Reddien-768x1024.png 768w, https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Peter-Reddien-225x300.png 225w, https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Peter-Reddien-1152x1536.png 1152w, https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Peter-Reddien-960x1280.png 960w, https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Peter-Reddien.png 1200w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \/>\n    <\/div>\n    <div class=\"offset-md-2 offset-lg-2 offset-xl-3 col-sm-16 col-md-12 col-lg-12 col-xl-10 py-4 px-0 collapse fade out order-3\" id=\"collapse-block_60361d543b80f\">\n      <p><strong>Positional Information and Repair of Skin Injury<\/strong><\/p>\n<p>The project aims to investigate if an untapped potential for true skin regeneration exists in vertebrates not known to have the capacity to regrow skin tissue. If indeed such capacity exists and if it can be reactivated it may be possible to regenerate fully functional skin without any scarring.<\/p>\n<p>Peter Reddien and his team at Whitehead Institute will look at the so-called \u201cregional identity\u201d of new cells which is central to regeneration in many animals capable of regeneration. They will use sophisticated techniques like single-cell RNA sequencing and spatial transcriptomics to compare factors and signaling pathways central to development in skin. Mouse skin &#8211; a vertebrate not known to be able to regenerate &#8211; and skin from a special regenerative salamander (axolotl) are used as models.<\/p>\n<p>Peter Reddien\u2019s research project is a basic skin science project with a novel approach to understanding the skin\u2019s potential for regeneration.<\/p>\n\n    <\/div>\n    <div class=\"offset-md-2 offset-lg-2 offset-xl-3 col-sm-16 col-md-12 col-lg-12 col-xl-10 border-wb order-4\"><\/div>\n  <\/div>\n<\/div>\n\n\n\n<div style=\"height:42px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"block-accordion-element accordion align\" data-block_60361a843b80b>\n  <div class=\"row\">\n    <div class=\"offset-md-2 offset-lg-2 offset-xl-3 col-sm-8 col-md-6 col-lg-6 col-xl-5 border-wt pl-0 order-1\">\n      <div class=\"d-flex flex-row align-items-center h-100\">\n        <button type=\"button\" class=\"btn btn-collapse collapsed p-0 mr-3\" data-toggle=\"collapse\" data-target=\"#collapse-block_60361a843b80b\" title=\"Click to expand\"><\/button>\n        <div class=\"d-flex flex-column justify-content-center\">\n          <h3>Simon Francis Thomsen<\/h3>\n                      <h5>Professor, Head of Department, Department of Dermatology, Bispebjerg Hospital, Denmark, DKK 2,6m<\/h5>\n                  <\/div>\n      <\/div>\n    <\/div>\n    <div class=\"col-sm-8 col-md-6 col-lg-6 col-xl-5 border-wt pr-0 order-sm-first order-first order-sm-2\">\n      <img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"1024\" src=\"https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Simon-1-768x1024.png\" class=\"w-100 h-auto\" alt=\"\" srcset=\"https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Simon-1-768x1024.png 768w, https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Simon-1-225x300.png 225w, https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Simon-1-1152x1536.png 1152w, https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Simon-1-960x1280.png 960w, https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Simon-1.png 1200w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \/>\n    <\/div>\n    <div class=\"offset-md-2 offset-lg-2 offset-xl-3 col-sm-16 col-md-12 col-lg-12 col-xl-10 py-4 px-0 collapse fade out order-3\" id=\"collapse-block_60361a843b80b\">\n      <p><strong>Global serum proteome profiling of hidradenitis suppurativa patients<\/strong><\/p>\n<p>The project aims to better understand the molecular basis of Hidradenitis Suppurativa (HS).\u00a0HS is a debilitating chronic skin disease characterized by the formation of painful nodules and abscesses predominantly in the armpits, groins, and buttocks. With time, the disease may progress resulting in persisting tunnels in the skin and pronounced scarring.\u00a0While there are many treatment options for HS, successful management often remains difficult and sometimes elusive \u2013 which likely reflects the still incompletely understood pathogenesis.<\/p>\n<p>Simon Francis Thomsen and his team will approach this by doing a large-scale, prospective study where they determine the protein composition of blood from more than 500 HS patients. They will follow the changes during disease progression (identified as Hurley stage I to III) to identify key biomarkers and signaling pathways specific for the disease.<\/p>\n<p>The\u00a0study\u00a0is a unique translational endeavor which\u00a0brings together clinical dermatologists with basic scientists to explore and characterize the serum proteome of patients with HS through analysis of blood serum samples obtained at the Department of Dermatology,\u00a0Bispebjerg\u00a0Hospital.<\/p>\n\n    <\/div>\n    <div class=\"offset-md-2 offset-lg-2 offset-xl-3 col-sm-16 col-md-12 col-lg-12 col-xl-10 border-wb order-4\"><\/div>\n  <\/div>\n<\/div>\n\n\n\n<div style=\"height:42px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"block-accordion-element accordion align\" data-block_60361b623b80c>\n  <div class=\"row\">\n    <div class=\"offset-md-2 offset-lg-2 offset-xl-3 col-sm-8 col-md-6 col-lg-6 col-xl-5 border-wt pl-0 order-1\">\n      <div class=\"d-flex flex-row align-items-center h-100\">\n        <button type=\"button\" class=\"btn btn-collapse collapsed p-0 mr-3\" data-toggle=\"collapse\" data-target=\"#collapse-block_60361b623b80c\" title=\"Click to expand\"><\/button>\n        <div class=\"d-flex flex-column justify-content-center\">\n          <h3>Yuval Rinkevich<\/h3>\n                      <h5>Principal Investigator, Helmholtz Zentrum M\u00fcnchen, Germany, DKK 3.7m<\/h5>\n                  <\/div>\n      <\/div>\n    <\/div>\n    <div class=\"col-sm-8 col-md-6 col-lg-6 col-xl-5 border-wt pr-0 order-sm-first order-first order-sm-2\">\n      <img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"1024\" src=\"https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Yuval-768x1024.png\" class=\"w-100 h-auto\" alt=\"\" srcset=\"https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Yuval-768x1024.png 768w, https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Yuval-225x300.png 225w, https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Yuval-1152x1536.png 1152w, https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Yuval-960x1280.png 960w, https:\/\/leo-foundation.org\/en\/wp-content\/uploads\/sites\/2\/2021\/09\/Yuval.png 1200w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \/>\n    <\/div>\n    <div class=\"offset-md-2 offset-lg-2 offset-xl-3 col-sm-16 col-md-12 col-lg-12 col-xl-10 py-4 px-0 collapse fade out order-3\" id=\"collapse-block_60361b623b80c\">\n      <p><strong>Finding a silver bullet to reduce scarring<\/strong><\/p>\n<p>The project aims to investigate the role of the skin fascia (a membrane structure in the skin) and its interplay with a specific type of \u201cscar-inducing\u201d cells to better understand \u2013 and subsequently prevent \u2013 formation of scars. These scar-inducing cells express a unique gene marker, but the cell biology and biochemistry driving the scar process are still unknown despite wounds being an extensively studied clinical challenge.<\/p>\n<p>Yuval Rinkevich and his team will use novel whole skin-fascia explants (scar-in-a-dish) along with fluorescent \u201cscar-forming\u201d cells that can be tracked during contracture scar formation using live imaging to understand the dynamics of the scar process. Along with single-cell RNA sequencing this will help reveal the cellular and molecular basis of the process and make way for a knowledge basis for its improvement in human skin.<\/p>\n<p>In addition, the project will investigate the potential of several FDA approved small molecules for treatment of contracture scars.<\/p>\n<p>The research has the potential to change our scientific and medical views of wound repair and open new therapeutic avenues to treat a variety of fibrotic skin conditions.<\/p>\n\n    <\/div>\n    <div class=\"offset-md-2 offset-lg-2 offset-xl-3 col-sm-16 col-md-12 col-lg-12 col-xl-10 border-wb order-4\"><\/div>\n  <\/div>\n<\/div>\n\n\n\n<div style=\"height:77px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-primary-coal-color has-primary-peach-background-color has-text-color has-background\" href=\"https:\/\/leo-foundation.org\/en\/projects-granted\/\" target=\"_blank\" rel=\"noreferrer noopener\">All grantees and awardees<\/a><\/div>\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n<div class=\"text-cols text-cols-columns-1 text-cols align\" data-block_603617303b809>\n  \n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<p><strong>Application and evaluation process<\/strong><\/p>\n\n\n\n<p>The LEO Foundation received a total of 28 applications from 14 different countries for this round. All applications were evaluated by the LEO Foundation\u2019s independent&nbsp;<a href=\"https:\/\/leo-foundation.org\/en\/grants-and-awards\/research-grants\/#sec\">Scientific Evaluation Committee<\/a>&nbsp; and the five projects described above were approved for funding by the LEO Foundation\u2019s Board of Trustees.<\/p>\n\n\n\n<p><strong>Next application round in 2022<\/strong><\/p>\n\n\n\n<p>The LEO Foundation calls for applications for research projects focusing on the skin and its diseases on an ongoing basis. The next application round opens in February 2022.<\/p>\n\n\n\n<p>The competition is open to talented skin researchers at PhD level or above from any country. The typical grant amount applied for is DKK 2-4 million for a period of 1-3 years. Researchers who would like to apply for a LEO Foundation research grant can&nbsp;<a href=\"https:\/\/leo-foundation.org\/en\/grants-and-awards\/research-grants\/\">apply here<\/a>.<\/p>\n<\/div><\/div>\n\n\n<\/div>\n\n<style type=\"text\/css\">\n  [data-block_603617303b809] p {\n    column-count: 1;\n    column-gap: 30px;\n  }\n<\/style>\n\n\n\n<div style=\"height:32px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-primary-coal-color has-primary-peach-background-color has-text-color has-background\" href=\"https:\/\/leo-foundation.org\/en\/grants-and-awards\/research-grants\/\" target=\"_blank\" rel=\"noreferrer noopener\">Learn more<\/a><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Can a mouse regrow damaged skin like a salamander can? Can we find a way towards scar-free wound healing? And can bacteria exchange treat acne while avoiding the issue of antibiotic resistance? <\/p>\n","protected":false},"author":4,"featured_media":4660,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-4646","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>The LEO Foundation awards DKK 14 million to five new skin research projects<\/title>\n<meta name=\"description\" content=\"Can a mouse regrow damaged skin like a salamander can? Can we find a way towards scar-free wound healing? 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