Beneficiaries: Professor Gregor B. Jemec, Department of Dermatology, Zealand University Hospital, Roskilde, Denmark, and Assoc. Professor Ole B. V. Pedersen, Department of Clinical Immunology, Næstved Hospital, Denmark
Grant: DKK 5.770.000
In this study, the group led by Professor Gregor Jemec of Roskilde Hospital has set out to identify new genes for the development of a long line of common dermatological conditions, including deep skin infections, warts, fungal infections, and eczema.
Many of these common skin diseases are still poorly understood and the treatments often insufficient. A study of the genetics of these disorders will help increase the understanding of the pathogenic mechanisms. The study will have its origin in Denmark and be based on unique national biobanks, national registries, and with extensive genetic analyses done in collaboration with deCODE Genetics, Iceland.
This is possible due to the growing number of Danish large-scale biobanks as well as biobank based scientific studies suited for further genetic studies. The largest genetic study in Denmark is the Danish Blood Donor Study (DBDS) in which the genome wide association (GWA) arrays have been analysed on 110,000 research participants.
In addition to this cohort, Jemec’s group is currently pursuing genetic testing on the Copenhagen Hospital Biobank (CHB) that includes samples from around 350,000 patients. Both of these biobanks have established a collaboration with deCODE Genetics, Iceland – one of the leading genetic research centers in the world.
Henrik Ullum, Professor, Department of Clinical Immunology, Rigshospitalet
Søren Brunak, Professor, Center for Protein Research (CPR), Copenhagen University
Simon Francis Thomsen, Professor, Department of Dermatology, Bispebjerg Hospital
Claus Zachariae, Professor, Department of Dermatology, Gentofte Hospital
Ingileif Jonsdottir, Professor, deCODE Genetics, Iceland
Errol Prens, Professor, Department of Dermatology, Erasmus University, Rotterdam, Netherlands
Christos Zouboulis, Professor, Department of Dermatology, Brandenburg Medical School Theodor Fontane, Dessau, Germany